Extracted from Jabuticaba peel through a sustainable process, preserving the natural synergy of bioactives from the plant matrix.
Below, the insulin signaling pathway in adipose and hepatic tissue, as well as proinflammatory cytokines, and the involvement of Longevity in these pathways. The flavonoids present in the product can improve insulin resistance by aiding in AKT activation, increasing FoxO1 phosphorylation, and inhibiting gluconeogenic enzyme transcription. Additionally, Longevity reduces cytokine expression by NFαB, reducing TNF-α pathway activation.
Composition
How to Use
SOURCES:
[1] Silva, J.K. (2017).
[2] Marostica, M. R. et al. (2017)
[3] Plaza, M. et al., (2016).
[4] Batista, Â. G. (2017).
[5] Baseggio, A. M. et al., (2018).
[6] Dragano, N. R. V. et al., (2013).
[7] Guo, H. et al., (2012).
[8] Leto, D. e Saltiel, A. R. (2012).